How Children's Advil® Products Compare

Learn about the differences between Children's Advil® and other pain relievers / fever reducers.

How Children's Advil® Products Compare

One basic question that many parents may have is, what's the difference between ibuprofen, the medicine in Children's Advil®, and acetaminophen, the medicine in Children's Tylenol®? Here are some things parents may want to know before they head to the drugstore:

  • Ibuprofen is the #1 pediatrician-recommended fever reducer/pain reliever.
  • Ibuprofen and acetaminophen are the only two active ingredients used in children's over-the-counter pain relievers/fever reducers.
  • Ibuprofen (the active ingredient in Children's Advil®) lasts longer than acetaminophen (the active ingredient in Children's Tylenol®). Ibuprofen lasts up to 8 hours, while acetaminophen lasts 4 - 6 hours.
  • Children's Advil® works faster* than Children's Tylenol®.
  • Ibuprofen and acetaminophen are both safe when taken as directed. However, as with any medication, parents should talk to their child's pediatrician to discuss what may be best for their child.
  • A recent analysis of more than 40 studies showed that when treating children's pain and fever, ibuprofen (the ingredient in Children's Advil®) works as good or better than acetaminophen (the ingredient in Children's Tylenol®).
  • Sometimes, when a child's fever is high, parents alternate between ibuprofen and acetaminophen to help break the fever. However, switching back and forth may lead to confusion and dosing errors, and there are no controlled studies supporting this practice.

* Based on reducing fever below 100°F.
Brands herein are trademarks of their respective owners.